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In the contrary, for the synthesis of protected, partially protected or very sensitive peptides the HYCRAM polymeric resin is more suitable 14.15 This method has the environmental advantage that there is no longer any need for strong acid as HF or trifluoroacetic acid to release any peptide acid, even fully protected from polymeric support

Several personal anecdotes praise its benefits in various areas

Tissue-specific distribution focuses activity

In short: injectable = more direct, possibly stronger acute effect

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